Her early paintings were primarily figurative socio-political works of people and primitive masks. Another series was large scale paintings of underwater scenes, tropical flowers and animal wildlife. Pacita's most extensive body of work, however, is her vibrant, colorful abstract work - many very large scale canvases, but also a number of small collages - on a range of materials from canvas and paper to bark cloth, metal, ceramics and glass. Abad created over 4,500 artworks. She painted a 55-meter long Alkaff Bridge in Singapore and covered it with 2,350 multicolored circles, just a few months before she died.
Abad developed a technique of trapunto painting (named after a quilting technique), which entailed stitching and stuffing her painted canvases to give them a three-dimensional, sculptural effect. She then began incorporating into the surface of her paintings materials such as traditional cloth, mirrors, beads, shells, plastic buttons and other objects.