
On January 29, 2018, Harris, along with Avery Bradley, Boban Marjanović, a future protected first-round draft pick and a future second-round draft pick, was traded to the Los Angeles Clippers in exchange for Blake Griffin, Willie Reed and Brice Johnson.[22][23] He made his debut for the Clippers on February 3, scoring 24 points in a 113–103 win over the Chicago Bulls.[24] On February 23, 2018, he recorded 30 points and 12 rebounds in a 128–117 win over the Phoenix Suns.
On November 15, 2018, Harris scored 18 points in a 116–111 win over the San Antonio Spurs, thus scoring at least 15 points in a career-best 14 straight games.[26] On November 25, he had 34 points and 11 rebounds in a 104–100 win over the Portland Trail Blazers. He was subsequently named Western Conference Player of the Week for games played Monday, November 19, through Sunday, November 25. It was his second career Player of the Week award. He also earned Western Conference Player of the Month for October and November, the first career Player of the Month honor of his career. On December 17, he scored a career-high 39 points in a 131–127 loss to the Trail Blazers. On January 20, he had 27 points, nine rebounds and nine assists in a 103–95 win over the Spurs.