Her mother initially gave her up for adoption, but later changed her mind. In 2006, Pierson earned a bachelor's degree in biology from the University of Texas at Dallas. After voting for Barack Obama in the 2008 presidential election, Pierson joined the Tea Party movement, becoming an activist.Pierson founded a local Tea Party group in Garland, Texas. She actively supported Ted Cruz in the 2012 Senate race in Texas and appeared on stage with him on election night. Pierson has previously served on several local committees, including one that advises Dallas Area Rapid Transit.
2014 Texas Congressional race - In the 2014 Texas Congressional elections, Pierson challenged incumbent Congressman Pete Sessions in the Republican primary to represent Texas' 32nd district.[citation needed] Her candidacy was endorsed by Rafael Cruz and Sarah Palin. While U.S. Senator Ted Cruz offered praise, he stopped short of an endorsement. In the election, she received 36 percent of the vote, losing to Sessions, who received 63 percent. Pierson went on to become spokesperson for the Tea Party Leadership Fund. In January 2015, Pierson attended a meeting for Tea Party activists in Myrtle Beach with Ted Cruz; while in Myrtle Beach, she also met with Donald Trump.
Pierson's tweet ran: "Perfect Obama's dad born in Africa, Mitt Romney's dad born in Mexico. Any pure breeds left?" During an interview on CNN, Pierson was asked if she wished to retract her comment; she declined, explaining, "I'm an activist and I am a half-breed. I'm always getting called a half-breed. And on Twitter when you're fighting with liberals and even establishment, you go back at them in the same silliness they are giving you. So, I myself am a half-breed." As of December 2015, Pierson served on the Texas Tea Party Caucus advisory committee.